The Yadav Lab aims to understand the molecular and cellular players dictating the survival and proliferation of pathogenic fungi in host cells under stress. Our primary focus is to understand the molecular mechanisms that allow fungal cells to adapt to higher temperatures, specifically enabling environmental fungi to grow and cause infections in humans.

We think that heat is not just a stress that fungi adapt to, but that high temperatures reshape cell division, genome stability, and pathogenicity in fungal pathogens. Decoding the underlying molecular and biochemical basis of heat response pathways will reveal the hidden biology of pathogenic fungi, identifying novel drug targets.